Microfluidic Microwave Sensor for Detecting Saline in Biological Range

A device for measuring biological small volume liquid samples in real time is appealing. One way to achieve this is by using a microwave sensor based on reflection measurement. A prototype sensor was manufactured from low cost printed circuit board (PCB) combined with a microfluidic channel made of polymethylsiloxane (PDMS). Such a sensor was simulated, manufactured, and tested including a vacuum powered sample delivery system with robust fluidic ports. The sensor had a broad frequency band from 150 kHz to 6 GHz with three resonance frequencies applied in sensing. As a proof of concept, the sensor was able to detect a NaCl content of 125 to 155 mmol in water, which is the typical concentration in healthy human blood plasma.

Authors:
Kilpijärvi Joni, Halonen Niina, Juuti Jari, Hannu Jari

Publication type:
A1 Journal article – refereed

Place of publication:

Keywords:
IDE, lab-on-a-chip, microfluidic sensing, RF sensor

Published:

Full citation:
Kilpijärvi, J.; Halonen, N.; Juuti, J.; Hannu, J. Microfluidic Microwave Sensor for Detecting Saline in Biological Range. Sensors 2019, 19, 819. https://doi.org/10.3390/s19040819

DOI:
https://doi.org/10.3390/s19040819

Read the publication here:
http://urn.fi/urn:nbn:fi-fe2019040411047